Job Summary

The Director, Translational Pathology will work across the Translational Science matrix to develop and implement pathology-based translational approaches to assessing PD and patient selection biomarkers for Oncology and Specialty Medicine programs. They will further serve as the scientific expert supporting digital pathology investigations and as a point of contact for developing and managing external partnerships in support of translational science and CDx programs. They will provide the expertise to create and integrate pathology datasets with broader multi-omic analyses to support hypothesis-driven translational research efforts with direct impact across the Development continuum. They will work in a highly collaborative environment.

Job Description

Responsibilities

Design and build internal digital pathology capabilities and support data generation for translational pathology evaluations across the portfolio. Develop and manage partnerships, largely focused on digital pathology, to support design and implementation of translational pathology plans. Lead development of the translational pathology strategic direction and support data generation for assigned assets, with a focus on the design and implementation of translational pathology plans. Provide expertise to the Daiichi Sankyo Global Research & Development organization to ensure access to state-of-the-art thinking on appropriate translational pathology strategies, evaluating their scientific basis and clinical applicability, the validation status and any technical or statistical issues related to proposed business plans. Communicate with portfolio leaders in Clinical Development, Discovery, QCP, CDx, RA, MA or other relevant functions to ensure effective integration of translational pathology strategy into broader Translational/Program strategies

Responsibilities Continued

Qualifications

Education Qualifications
MD or MD/PhD with Anatomic/Clinical Pathology board certification required 

Experience Qualifications

• 5 or more years of post-doctoral and relevant industry experience with expertise in pathology-driven translational research, biomedical leadership and human translational research in clinical trials required. required
• Experience with digital/computational pathology technologies and translational research required 
• Extensive experience in the discovery, characterization and utilization of innovative translational strategies across the continuum of preclinical and clinical stages preferred.
• Experience/knowledge in companion diagnostics device development preferred 
• Demonstrated ability to define clear translational strategies anchored in disease biology and drug mechanism of action, aligned with clinical development required
• Deep knowledge in pathology-based and other biomarker technologies including immunohistochemistry (monoplex and multiplex), digital pathology, spatial analyses, NGS, immunoassay, proteomics including expertise in assay validation required

Travel Requirements
Ability to travel up to 10% of the time. Global travel

Additional Information